The relationship of E-selectin singlenucleotide polymorphisms with breast cancer in Iraqi Arab women

Breast cancer (BC) is a significant threat to female health, with both modifiable andnon-modifiable risk factors. It is essential to monitor patients regularly and to raise population awareness. Increasing research also suggests that E-selectin (SELE) may increase tumor angiogenesis and the development of cancer. This study investigated SELE single-nucleotide polymorphisms (SNPs) in the following positions: rs5367T/C, rs5368C/T, rs5362T/G,and rs5362T/C. Using polymerase chain reaction, significant differences in allele and genotype frequencies were found between BC patients and controls. Position rs5368 was associated with an increased risk of BC for the CT and TT genotypes, with odds ratios (ORs) of16.3 and 6.90 (Fisher probability = 0.0001, p = 0.005). Women with the T allele had a 19.3-fold higher incidence of BC, while allele C may be a protective allele against BC (OR, 0.05).Heterozygous genotypes at rs5367, rs5362, and rs5362 were significantly more common inBC patients, with ORs of 5.70, 4.50, and 3.80, respectively. These SNPs may be associatedwith the risk of BC, because the frequency of mutant alleles was significantly higher in patients (OR: 4.26, 3.83, and 4.30, respectively) than in controls (OR: 0.23, 0.30, and 0.20, respectively). These SNPs may be considered a common genotype in the Iraqi population,with the wild-type allele having a protective fraction and the mutant allele having an environmental fraction. The results also revealed a 2-fold increase in gene expression in BCpatients compared to controls, with a significant effect (p = 0.017). This study's findingsconfirm the importance of SELE polymorphisms in cancer risk prediction.

Associations between single-nucleotide polymorphisms of the interleukin-18 gene and breast cancer in Iraqi women

According to long-term projections, by 2030, the world’s population is predicted to reach 7.5 billion individuals, and there will be roughly 27 million new cancer cases diagnosed. The global burden of breast cancer (BC) is expected to rise. According to the Ministry of Health-Iraqi Cancer Registry, cancer is the second largest cause of death after cardiovascular disease. This study investigated the interleukin-18 (IL18) single-nucleotide polymorphisms (SNPs) –607C/A rs1946518 and –137G/C rs187238 using the sequence-specific amplification-polymerase chain reaction approach. Regarding the position –607C/A, there was a highly significant difference between the observed and expected frequencies in patients and controls (χ 2 = 3.16 and χ 2 = 16.5), respectively. The AA and CA genotypes were associated with significantly increased BC risk (odds ratio [OR], 3.68; p = 0.004 and OR, 2.83; p = 0.04, respectively). Women with the A allele had a 5.03-fold increased susceptibility to BC. The C allele may be a protective allele against BC (OR, 0.19). Although position –137G/C showed no significant differences in the CC genotype distribution (p = 0.18), the frequency of the CC genotype was significantly higher in patients than in controls. In contrast, patients had a significantly higher frequency of GC genotypes than controls (p = 0.04), which was associated with an increased risk of developing BC (OR, 2.63). The G allele frequency was significantly lower in patients than in controls (55.0% vs. 76.2%, respectively). This SNP may be considered a common genotype in the Iraqi population, with the wild-type G allele having a protective function (OR, 0.19) and the mutant C allele having an environmental effect (OR, 2.63).

Green-synthetized selenium nanoparticles using berberine as a promising anticancer agent / 中西医结合学报

OBJECTIVE@#The chemo-preventative and therapeutic properties of selenium nanoparticles (SeNPs) have been documented over recent decades and suggest the potential uses of SeNPs in medicine. Biogenic SeNPs have higher biocompatibility and stability than chemically synthesized nanoparticles, which enhances their medical applications, especially in the field of cancer therapy. This study evaluated the potential of green-synthetized SeNPs by using berberine (Ber) as an antitumor agent and elucidated the mechanism by which these molecules combat Ehrlich solid tumors (ESTs).@*METHODS@#SeNPs containing Ber (SeNPs-Ber) were synthesized using Ber and Na@*RESULTS@#Treatment with SeNPs-Ber significantly improved the survival rate and decreased the body weight and tumor size, compared to the EST group. SeNPs-Ber reduced oxidative stress in tumor tissue, as indicated by a decrease in the lipid peroxidation and nitric oxide levels and an increase in the glutathione levels. Moreover, SeNPs-Ber activated an apoptotic cascade in the tumor cells by downregulating the B-cell lymphoma 2 (Bcl-2) expression rate and upregulating the Bcl-2-associated X protein and caspase-3 expression rates. SeNPs-Ber also considerably improved the histopathological alterations in the developed tumor tissue, compared to the EST group.@*CONCLUSION@#Our study provides a new insight into the potential role of green-synthesized SeNPs by using Ber as a promising anticancer agent, these molecules could be used alone or as supplementary medication during chemotherapy.

Morphological and molecular identification of Cladosporium sphaerospermum isolates collected from tomato plant residues / Identificação morfológica e molecular de isolados de Cladosporium sphaerospermum coletados de resíduos de plantas de tomate

This study was conducted at the Agriculture College University of Karbala, Iraq to isolate and morphologically and molecularly diagnose thirteen Cladosporium isolates collected from tomato plant residues present in desert regions of Najaf and Karbala provinces, Iraq. We diagnosed the obtained isolates by PCR amplification using the ITS1 and ITS4 universal primer pair followed by sequencing. PCR amplification and analysis of nucleotide sequences using the BLAST program showed that all isolated fungi belong to Cladosporium sphaerospermum. Analysis of the nucleotide sequences of the identified C. sphaerospermum isolates 2, 6, 9, and 10 showed a genetic similarity reached 99%, 98%, 99%, and 99%, respectively, with those previously registered at the National Center for Biotechnology Information (NCBl). By comparing the nucleotide sequences of the identified C. sphaerospermum isolates with the sequences belong to the same fungi and available at NCBI, it was revealed that the identified C. sphaerospermum isolates 2, 6, 9, and 10 have a genetic variation with those previously recorded at the National Center for Biotechnology Information (NCBl); therefore, the identified sequences of C. sphaerospermum isolates have been registered in GenBank database (NCBI) under the accession numbers MN896004, MN896107, MN896963, and MN896971, respectively.

Este estudo foi conduzido na Agriculture College University of Karbala, Iraque, para isolar e diagnosticar morfológica e molecularmente treze isolados de Cladosporium coletados de resíduos de plantas de tomate presentes nas regiões desérticas das províncias de Najaf e Karbala, no Iraque. Diagnosticamos os isolados obtidos por amplificação por PCR usando o par de primers universais ITS1 e ITS4 seguido de sequenciamento. A amplificação por PCR e a análise de sequências de nucleotídeos usando o programa BLAST mostraram que todos os fungos isolados pertencem a Cladosporium sphaerospermum. A análise das sequências de nucleotídeos dos isolados 2, 6, 9 e 10 de C. sphaerospermum identificados mostrou similaridade genética de 99%, 98%, 99% e 99%, respectivamente, com aqueles previamente registrados no National Center for Biotechnology Informações (NCBl). Ao comparar as sequências de nucleotídeos dos isolados de C. sphaerospermum identificados com as sequências pertencentes aos mesmos fungos e disponíveis no NCBI, foi revelado que os isolados 2, 6, 9 e 10 de C. sphaerospermum identificados têm variação genética com aqueles anteriormente registrados no National Center for Biotechnology Information (NCBl). Portanto, as sequências identificadas de isolados de C. sphaerospermum foram registradas no banco de dados GenBank (NCBI) sob os números de acesso MN896004, MN896107, MN896963 e MN896971, respectivamente.

Morphological and molecular identification of Cladosporium sphaerospermum isolates collected from tomato plant residues

Abstract This study was conducted at the Agriculture College University of Karbala, Iraq to isolate and morphologically and molecularly diagnose thirteen Cladosporium isolates collected from tomato plant residues present in desert regions of Najaf and Karbala provinces, Iraq. We diagnosed the obtained isolates by PCR amplification using the ITS1 and ITS4 universal primer pair followed by sequencing. PCR amplification and analysis of nucleotide sequences using the BLAST program showed that all isolated fungi belong to Cladosporium sphaerospermum. Analysis of the nucleotide sequences of the identified C. sphaerospermum isolates 2, 6, 9, and 10 showed a genetic similarity reached 99%, 98%, 99%, and 99%, respectively, with those previously registered at the National Center for Biotechnology Information (NCBl). By comparing the nucleotide sequences of the identified C. sphaerospermum isolates with the sequences belong to the same fungi and available at NCBI, it was revealed that the identified C. sphaerospermum isolates 2, 6, 9, and 10 have a genetic variation with those previously recorded at the National Center for Biotechnology Information (NCBl); therefore, the identified sequences of C. sphaerospermum isolates have been registered in GenBank database (NCBI) under the accession numbers MN896004, MN896107, MN896963, and MN896971, respectively.

Resumo Este estudo foi conduzido na Agriculture College University of Karbala, Iraque, para isolar e diagnosticar morfológica e molecularmente treze isolados de Cladosporium coletados de resíduos de plantas de tomate presentes nas regiões desérticas das províncias de Najaf e Karbala, no Iraque. Diagnosticamos os isolados obtidos por amplificação por PCR usando o par de primers universais ITS1 e ITS4 seguido de sequenciamento. A amplificação por PCR e a análise de sequências de nucleotídeos usando o programa BLAST mostraram que todos os fungos isolados pertencem a Cladosporium sphaerospermum. A análise das sequências de nucleotídeos dos isolados 2, 6, 9 e 10 de C. sphaerospermum identificados mostrou similaridade genética de 99%, 98%, 99% e 99%, respectivamente, com aqueles previamente registrados no National Center for Biotechnology Informações (NCBl). Ao comparar as sequências de nucleotídeos dos isolados de C. sphaerospermum identificados com as sequências pertencentes aos mesmos fungos e disponíveis no NCBI, foi revelado que os isolados 2, 6, 9 e 10 de C. sphaerospermum identificados têm variação genética com aqueles anteriormente registrados no National Center for Biotechnology Information (NCBl). Portanto, as sequências identificadas de isolados de C. sphaerospermum foram registradas no banco de dados GenBank (NCBI) sob os números de acesso MN896004, MN896107, MN896963 e MN896971, respectivamente.

Morphological and molecular identification of Cladosporium sphaerospermum isolates collected from tomato plant residues / Identificação morfológica e molecular de isolados de Cladosporium sphaerospermum coletados de resíduos de plantas de tomate

This study was conducted at the Agriculture College University of Karbala, Iraq to isolate and morphologically and molecularly diagnose thirteen Cladosporium isolates collected from tomato plant residues present in desert regions of Najaf and Karbala provinces, Iraq. We diagnosed the obtained isolates by PCR amplification using the ITS1 and ITS4 universal primer pair followed by sequencing. PCR amplification and analysis of nucleotide sequences using the BLAST program showed that all isolated fungi belong to Cladosporium sphaerospermum. Analysis of the nucleotide sequences of the identified C. sphaerospermum isolates 2, 6, 9, and 10 showed a genetic similarity reached 99%, 98%, 99%, and 99%, respectively, with those previously registered at the National Center for Biotechnology Information (NCBl). By comparing the nucleotide sequences of the identified C. sphaerospermum isolates with the sequences belong to the same fungi and available at NCBI, it was revealed that the identified C. sphaerospermum isolates 2, 6, 9, and 10 have a genetic variation with those previously recorded at the National Center for Biotechnology Information (NCBl); therefore, the identified sequences of C. sphaerospermum isolates have been registered in GenBank database (NCBI) under the accession numbers MN896004, MN896107, MN896963, and MN896971, respectively.

Este estudo foi conduzido na Agriculture College University of Karbala, Iraque, para isolar e diagnosticar morfológica e molecularmente treze isolados de Cladosporium coletados de resíduos de plantas de tomate presentes nas regiões desérticas das províncias de Najaf e Karbala, no Iraque. Diagnosticamos os isolados obtidos por amplificação por PCR usando o par de primers universais ITS1 e ITS4 seguido de sequenciamento. A amplificação por PCR e a análise de sequências de nucleotídeos usando o programa BLAST mostraram que todos os fungos isolados pertencem a Cladosporium sphaerospermum. A análise das sequências de nucleotídeos dos isolados 2, 6, 9 e 10 de C. sphaerospermum identificados mostrou similaridade genética de 99%, 98%, 99% e 99%, respectivamente, com aqueles previamente registrados no National Center for Biotechnology Informações (NCBl). Ao comparar as sequências de nucleotídeos dos isolados de C. sphaerospermum identificados com as sequências pertencentes aos mesmos fungos e disponíveis no NCBI, foi revelado que os isolados 2, 6, 9 e 10 de C. sphaerospermum identificados têm variação genética com aqueles anteriormente registrados no National Center for Biotechnology Information (NCBl). Portanto, as sequências identificadas de isolados de C. sphaerospermum foram registradas no banco de dados GenBank (NCBI) sob os números de acesso MN896004, MN896107, MN896963 e MN896971, respectivamente.

Chronic progressive external ophthalmoplegia in a Saudi patient with a mutation in the POLG gene successfully managed with bilateral frontalis sling

Chronic progressive external ophthalmoplegia (CPEO) is a complex slowly progressive mitochondrial disorder characterized by extraocular muscle weakness with or without multisystem involvement. The mainstay of therapy in a patient with CPEO is supportive. However, in moderate cases, surgery might be indicated including surgeries for ptosis and strabismus. In this article, we report a Saudi patient with CPEO due to compound heterozygous variants in the DNA polymerase gamma (POLG) gene c.2246T>C p.(Phe749Ser) and c.1735C>T p.(Arg579Trp), which are classified as pathogenic. Proper diagnosis with genetic testing confirmation is important to guide the management and counsel the patient about the prognosis and the management options. The patient was successfully managed with bilateral frontalis sling and illustrates the importance of surgical intervention to improve vision and cosmetic appearance in patients with CPEO. We emphasize the importance of multidisciplinary care in the management of cases of mitochondriopathy, especially CPEO.

Factors Associated With Stress And Depression Among Family Medicine Residents In Al Madinah, Saudi Arabia

@#Stress and depression among physicians are recognized as important problems because of the potential risks they impose on individual health and medical care. This study aims to assess level of stress and depression and associated factors among family medicine residents in Al-Madinah, Saudi Arabia. Methods: This cross-sectional study was conducted among 75 residents in the family medicine residency programs in Al-Madinah. Stress and depression were assessed by using the stress and depression subscales of the validated Depression, Anxiety and Stress Scale-21 item (DASS-21). Sources of stress were assessed by 22 items. Results: Most participants had stress (57.3%) and depression (53.3%). Stress was associated with work overload (P=0.032), work demands affect personal/home life (P<0.001), inability to participate in decision making (P=0.026) and inability to make full use of skills and abilities (P=0.019). Depression was associated with ‘work demands affect personal/home life’ (P<0.001). Conclusion: The prevalence of stress and depression among family resident doctors was high. Establishing a residency counseling office is suggested to deal with the resident's problems in a way that supports their needs and leads to the best working environment.

Self-Medication Practice among Amman’s Householders: Prevalence and Factors

Aims:This study is set out to explore the prevalence and the influencing factors of self-medication practice, besides, to assess the knowledge levels of Amman’s householders.Methods:A community-based cross-sectional study was conducted using pre-tested questionnaires. The householders (n=601) were randomly selected from two disparate regions in Amman (West and East), which reflect different segments of the society.Results:Self-medication was practised by more than half (53.1%) of Amman’s Householders. The East of Amman householders shows a relatively lower rate (49.7%) of self-medication than the West of Amman ones (56.5%), which can be attributed to the higher ability to pay for medicines and a higher level of knowledge among West residents that might allow them to go directly to the pharmacies without consulting a physician. The relatively severe illness (e.g. respiratory diseases and eye complaints) showed the lowest influence for self-medication, which indicates a good level of awareness about the importance of consulting the health care professionals. Furthermore, the two main reasons for self-medication were experiencing a good result from previous self-medication (87.8%) and saving time (84.6%). The self-medication practice was associated with the education level and the knowledge level; the knowledge level of West of Amman residents was correlated positively with the self-medication practice prevalence; nevertheless, East ones presented a less notable pattern.Conclusion:There is a knowledge gap regarding the proper SM practice, the health professionals must effectively educate the patients regarding the responsible self-medication practice and thus limit the adverse outcomes

Assessment of hand hygiene practices among rural population in Davangere

Background: Handwashing is well-recognized preventive tool for disease prevention. Handwashing with soap has been viewed as one of the most cost-effective ways of reducing the global infectious disease burden. Hence, the present study was conducted with an aim to study handwashing practices in rural communities. Objectives: The objectives are as follows: (i) To assess the handwashing practices in rural areas, (ii) to identify the factors associated with handwashing practices, and (iii) to determine the association between handwashing and certain infections. Materials and Methods: A cross-sectional study was conducted among 128 respondents, residing in Kukkuwada village, Davangere Taluk. Data were collected by house to house surveys using semi-structured and pre-tested questionnaire. Data were entered into Microsoft Excel and analyzed using SPSS version 16.0. Results: A total of 128 (44 males and 84 females) individuals participated in the study. The majority were from 21 to 40 years age-group (49.2%). All of them practiced handwashing after defecation. A majority, 80 (62.5%) were using soap and water, 12 (9.4%) used water and antiseptic solution for handwashing, and 36 (28.1%) used only water for handwashing. Handwashing practices (medium and technique) were significantly associated with history of episode of diarrhea and upper respiratory tract infection in the past 3 months. Conclusions: Among all the study participants who practiced handwashing, majority of them used water with soap and is influenced by factors such as age, frequency of health facility visits, and previous infections. The findings were found encouraging, and we recommend measures for sustainable practice.

Infective Endocarditis Diagnosis and Management

Background: Infective endocarditis (IE) is a microbial (usually bacteria) infection affecting the heart tissue orthe adjacent vascular endothelium. The blood-circulating microbes usually need to be available in a certaininoculum to allow invasion and thus infect the heart. Moreover, if the valve annulus is affected, the infection willspread into the extravascular areas. The main causative agents in IE are bacteria; however, other causes such asfungi are still a possibility in many cases. The most common bacteria seen are staphylococci and streptococci,and they collectively account for approximately 80% of cases; while S. Aureus, in particular is the most aggressiveone. Objectives: We aimed to review the literature regarding the pathophysiology of infective endocarditis,clinical features, risk factors, diagnosis, and management of this disease. Methodology: PubMed database wasused for articles selection. Conclusion: Diagnosing of infective endocarditis remains the pivotal step inmanagement of these patients; thus, it had been studied widely for many years. Duke or modified Duke Criteriaremain the most famous tool in diagnostic assessment, and they incorporate information from multiple sourcesinto minor and major criteria which will reflect the probability of the disease in the suspected patients. Themainstay treatment of infective endocarditis is intravenous antibiotics, titred to serum levels, and the choicedepends on the suspected causative organism and the valve involved in IE being native or prosthetic. Infectiveendocarditis prophylaxis is still a major point of difference among clinicians. Some institutions advocate forantibiotic prophylaxis in patients undergoing any dental procedure; while, others advised against prophylacticantibiotic.

Evaluation of Contrast-Induced Acute Kidney Injury (CI-AKI)

Background: The risk of contrast-induced acute kidney injury (CI-AKI) has been accepted lately by medicalliterature and practice since it is the third leading cause of acute kidney injury in hospitalized patients. Differentmeasures in practice are being used to prevent the incidence of CI-AKI. Objective: In this review, we aimed todiscuss the different methods of prevention of CI-AKI mentioned in the literature. Methods: A comprehensivesearch was done using biomedical databases including Medline, and PubMed, for studies concerned with theassessment of Contrast-Induced Acute Kidney Injury. Keywords used in our search through the databases were“Contrast-Induced Kidney Failure” and “Diagnosis & Management”. Conclusion: Intravenous (IV) fluidhydration is the mainstay of practice in the prevention of CI-AKI. Intravenous administration of sodiumbicarbonate has also gained notable importance in the prevention of CI-AKI, but it is still not confirmed. Despitethat the application of N-acetyl cysteine to prevent CI-AKI is controversial, N-acetyl cysteine remains a commonlyutilized agent even without solid scientific evidence. The application of statins for the prevention of CI-AKI afterintravascular contrast medium administration revealed some promising results but it is still premature toimplement their application in daily clinical practice. Therefore, there is a need for additional well designed andsufficiently powered randomized controlled trials to clarify these issues and to assess the risk vs benefit of allother methods for the purpose of CI-AKI prevention

Evaluation of Diagnosis and Management of Anaphylactic shock in Emergency Room

Background: Anaphylaxis is the most severe form of an allergic reaction. The incidence rate of anaphylaxisenhanced during the last decade. Death may happen in fatal anaphylactic shocks within minutes of the reaction.Hence, it is needed to highlight the significance of effective emergency management. Objective: In thisinvestigation, we aimed to discuss the important aspects of anaphylaxis shock diagnosis and management in theemergency room. Method: PubMed database was used for article selection, and the following keywords wereused in the mesh: "anaphylaxis management in emergency room"[Mesh] and “anaphylactic shock managementin emergency room"[Mesh]. A total of 20 papers were reviewed and included in the research. Conclusion: Theessential manifestations of anaphylactic reactions are on the skin, in the gastrointestinal tract, respiratory tract,and cardiovascular system. The symptoms may begin and progress very quickly, in which the condition candeteriorate dramatically into death within a few minutes. Then, a physician should be skilled and prepared forsuch cases. The most noteworthy drug in the acute remedy of anaphylaxis is adrenaline as it is a lifesaving drugin cases of anaphylaxis.

Molecular detection and antimicrobial resistance of Clostridium perfringens isolated from diabetic patients and bullet wounds

Clostridium perfringens is a major cause of gas gangrene. The morbidity of C. perfringens is connected with producing toxins. This cross-sectional study was designed to isolate, genetically diagnose, and study the antibiotic susceptibility patterns of C. perfringens isolated from clinical samples. Different wound swabs (from diabetic patients, cellulitis, and bullet wounds) were taken from 140 patients. For isolation of anaerobic bacteria, samples (in thioglycolate broth) were immediately incubated anaerobically then identified according to the cultural properties and biochemical tests. DNA was extracted from all specimens. Polymerase chain reaction was applied for detection of 16SrRNA and internal transcribed spacer (ITS) genes of C. perfringens. The susceptibility of bacterial isolates to different antibiotics was determined using Vitek 2 system and disk diffusion test. Out of 140 clinical samples collected during this study, 3 (2.14%) C. perfringens isolates were recovered of which 2 isolates (1.43%) obtained from diabetic patients and one (0.71%) from bullet wounds. Results also showed that only 7 isolates (5%) were detected by a molecular method using specific primers 16S rRNA and ITS genes of C. perfringens. Results of antibiotic susceptibility testing showed that all isolates were highly susceptible to penicillins and β-lactamase inhibitors, metronidazole, and aminoglycosides. On the other hand, all isolates were highly resistant to tetracycline, levofloxacin, and erythromycin. The susceptibility patterns of C. perfringens isolates showed that all isolates were multidrug resistance. Using the amplification of ITS gene increases specificity and sensitivity (by reducing non-specific annealing and primer dimer formation) which increases the probability of detection of suspected C. perfringens isolates.

Eurycoma longifolia Root Aqueous Extract Augments the Testosterone Level and Spermatogenesis in Adult Male Rats

@#Introduction The Eurycoma longifolia (EL) root aqueous extract has long been used as an enhancer of male sexual performance. However, data from previous studies in both human males and experimental male animals on the testosterone level in those given the EL extract orally were at best insufficiently conclusive. Materials and Method Sixty-four healthy adult male Sprague Dawley rats were acclimatized, and randomized into six test groups and one control group. All rats where given either the aqueous EL extract or distilled water via metal gavage needle. The first three test groups received the low (50mg/kg bw), medium (100mg/ kg bw) and high (200mg/kg bw) doses respectively of the EL daily for 15 days only. The second three test groups continued receiving the same daily treatment doses for 30 days. The controls were given distilled water only. At the end of each of the study period, blood samples were collected via cardiac puncture and the rats were euthanized. The testicles were obtained, weighed, and processed for histological examination. Results The sera testosterone levels were higher in animals which received the medium and high doses for both treatment duration. Rats which received medium and high oral doses of EL showed an increase of spermatogenesis and mature spermatozoa. Conclusion The optimal enhancing effect on sera testosterone levels and testicular spermatogenesis of EL treatment in adult male rats was observed with the medium dose of 100mg/kg bw given once daily for both 15 and 30 days.

2-amino-6-chlorobenzothiaozole as effective corrosion inhibitor for copper in acidic media / 国际药学研究杂志

This research is studied effect of "2-amino-6-chlorobenzothiaozole as effective corrosion inhibitor for copper in acidic media" by using weight Loss and polarization methods. Acid used is HCl, temperatures conditions varied between 45-65 oC and concentrations of inhibitors within range 100-250 ppm.Results showed that "2-amino-6-chlorobenzothiaozole "is good inhibitor for copper metal, and increasing the efficiency of inhibition of the process thus decrease both the potential and current density, lead to increased surface coverage of corrosion inhibitor. The reason for the good adsorption of the inhibitor is the presence of groups of nitrogen and sulfur in the structural composition of this type of inhibitor and production film layer. The study is study effects of the inhibitor on thermodynamics kinetic parameters ΔS, Ea, Δ Gads and ΔH.

Concha bullosa, nasal septal deviation, and their impacts on maxillary sinus volume among Emirati people: A cone-beam computed tomography study

PURPOSE: To determine the prevalence of concha bullosa (CB) and nasal septal deviation (NSD) and their impact on maxillary sinus volume (MSV). MATERIALS AND METHODS: Cone-beam computed tomographic (CBCT) images of 106 Emirati people were used in this study. The direction and angle of septal deviation were calculated. The presence of CB, which could be unilateral, contralateral, or bilateral in relation to the direction of NSD, was also recorded. MSV was measured using reconstructed Digital Imaging and Communication in Medicine images on Dolphin 3D imaging software version 11.8 premium (Dolphin Imaging, Chatsworth, CA, USA). P values<0.05 were considered to indicate statistical significance. RESULTS: CB was detected in 37.7% of the sample; 20.7% of the sample showed single unilateral CB and 16.6% had single bilateral CB. NSD was seen in 74.5% of the sample. In the participants with CB, 45.5% showed mild deviation, 34.4% showed moderate deviation, and only 12.5% showed severe septal deviation. CB, but not NSD, was associated with significantly higher MSV on the affected side (P=0.001). CONCLUSION: Although NSD was observed in more than two-thirds of the sample and CB was present in more than one-third of the sample, only CB had a significant impact on MSV.

A Systematic Review and Meta-analysis of Randomized Controlled Trials Comparing Surgical versus Conservative Treatments for Acute Undisplaced or Minimally-Displaced Scaphoid Fractures

BACKGROUND: Surgical and conservative methods have been reported by various studies for high rates of fracture union and subsequent regain of function among patients with undisplaced or minimally-displaced scaphoid fractures. Hence, this study aims to analyze the best available evidence to comprehend the relative benefits and risks of these therapeutic options. METHODS: A systematic search of the literature from different databases and search engines was performed with strict eligibility criteria to obtain the highest quality of evidence. All randomized controlled trials delineating the outcomes of surgical versus conservative treatments for acute undisplaced or minimally-displaced scaphoid fractures were included and then evaluated using scoring tools: Cochrane risk of bias tool and PEDro scale. Data were pooled using random-effects models with standard mean differences for continuous outcomes and risk ratios for dichotomous variables. RESULTS: The search yielded 339 potentially related articles, further trimmed down to eight studies based on the eligibility criteria. The meta-analysis revealed that surgical treatment resulted in significantly better functional outcomes than conservative treatment. Furthermore, surgery resulted in the prevention of delayed union of fractures and reduction of time needed to return to work. CONCLUSIONS: While four studies reported advantages of surgical treatment, evidence was insufficient to provide a definitive conclusion that surgery is a better option. Due to the significant limitations with respect to certain variables, the superiority of one method to the other could not be established.

rare cause of pneumoperitoneum - a ruptured infected endometriotic cyst

Pneumoperitoneum is a surgical emergency that results from gastrointestinal tract perforation, most commonly perforation of the duodenum caused by peptic ulcer. It rarely results from nonsurgical causes. We present a case of rupture infected endometriotic cyst that was presented as acute abdomen with pneumoperitoneum in which exploratory laparotomy was done with salpingooophrectomy

rare large low rectal melanoma

Rectal melanoma is a very rare and fatal disease. In this report, we present the case of a 49-year-old lady who was presented with bleeding per rectum. Examination and investigations revealed a low rectal melanoma with metastasis. A wide local excision of the bleeding mass was done